[V10K]kalata B1(936) Protein Card

General Information
Name [V10K]kalata B1
Sequence GLPVCGETCKGGTCNTPGCTCSWPVCTRN
Class Cyclotide
Average Mass 2921.32
Monoisotopic Mass 2919.17
m/z M+H 2921.32
ProteinType Mutant
Parent kalata B1
Organism Synthetic
Notes Inactive against T cell proliferation, cytokine secretion. Did not improve clinical score in EAE-induced mouse model of MS.
Cyclic Yes

Assay
No assays found

References
Thell K, Hellinger R, Sahin E, Michenthaler P, Gold-Binder M, Haider T, Kuttke M, Liutkevi?i?t? Z, G√∂ransson U, Gr√ľndemann C, Schabbauer G, Gruber CW (2016) Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis Proc Natl Acad Sci USA 113:3960-3965

Cross-references
Nucleic acids
Structure
Links

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