SFTI-1(6,5)(83) Protein Card

General Information
Name SFTI-1(6,5)
Sequence GRCTKSIPPICFPD
Class BBI-like trypsin inhibitor
Average Mass 1531.81
Monoisotopic Mass 1530.74
m/z M+H 1531.75
ProteinType Acyclic permutant
Parent SFTI-1
Organism Synthetic
Notes Acyclic permutant between residue 5 and 6
Cyclic No

Assay
Protease inhibition
SFTI-1(6,5) shown to have trypsin inhibitory activity and is cyclised after incubation with trypsin. [...]Marx UC et al. (2003) J Biol Chem 278:21782-9
NOE Restraint
NOE restraints for 1O8Z [...]
NOE restraints for 1O8Y [...]

References
Marx UC, Korsinczky ML, Schirra HJ, Jones A, Condie B, Otvos L Jr, Craik DJ (2003) Enzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide. J Biol Chem 278:21782-9

Cross-references
Nucleic acids
Structure SFTI-1(6,5)
SFTI-1(6,5)
Links

Tools