([Lys(Ac)]2[Arg(CHD)])cyO2(239) Protein Card

General Information
Name ([Lys(Ac)]2[Arg(CHD)])cyO2
Sequence GIPCGESCVWIPCISSAIGCSCXSXVCYXN
Class Cyclotide
Average Mass NA
Monoisotopic Mass 0
m/z M+H 0
ProteinType Mutant
Parent cycloviolacin O2
Organism Synthetic
Notes Modified lysines and arginine
Cyclic Yes

Assay
Cancer Cell Toxicity
Glutamic acid mutant had reduced activity [...]Herrmann A et al. (2006) Cell Mol Life Sci 63:235-45

References
Herrmann A, Svangard E, Claeson P, Gullbo J, Bohlin L, Goransson U (2006) Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2. Cell Mol Life Sci 63:235-45

Cross-references
Nucleic acids
Structure
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