[R10]oMCoTI-II(230) Protein Card

General Information
Name [R10]oMCoTI-II
Sequence GVCPKILKKCRRDSDCPGACICRGNGYCG
Class Squash trypsin inhibitor
Average Mass 3067.61
Monoisotopic Mass 3065.38
m/z M+H 3066.39
ProteinType Mutant
Parent MCoTI-II
Organism Synthetic
Notes Open chain variant, truncated, substituted
Cyclic No

Assay
Protease inhibition
Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]Avrutina O et al. (2005) Biol Chem 386:1301-6

References
Avrutina O, Schmoldt H, Gabrijelcic-Geiger D, Le Nguyen D, Sommerhoff CP, Diederichsen U, Kolmar H (2005) Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II. Biol Chem 386:1301-6

Cross-references
Nucleic acids
Structure
Links

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