[Ser3,11]aSFTI-1(217) Protein Card

General Information
Name [Ser3,11]aSFTI-1
Sequence GRSTKSIPPISFPD
Class BBI-like trypsin inhibitor
Average Mass 1501.71
Monoisotopic Mass 1500.8
m/z M+H 1501.81
ProteinType Acyclic permutant
Parent SFTI-1
Organism Synthetic
Notes Acyclic analogue with serines replacing cysteins.
Cyclic No

Assay
Protease inhibition
Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]Guo X et al. (2006) Chem Biol Drug Des 68:341-4

References
Guo X, Shi J, Tang Z, Cui D, Zhang Y (2006) Synthesis and biological activity of seleno sunflower trypsin inhibitor analog. Chem Biol Drug Des 68:341-4

Cross-references
Nucleic acids
Structure
Links

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