[(R,S)HmVal5]SFTI-1(200) Protein Card

General Information
Name [(R,S)HmVal5]SFTI-1
Sequence GRCTXSIPPICFPD
Class BBI-like trypsin inhibitor
Average Mass 1532.80
Monoisotopic Mass 0
m/z M+H 0
ProteinType Acyclic permutant
Parent SFTI-1
Organism Synthetic
Notes Acyclic analogue with (R,S)-?-hydroxymethylvaline
Cyclic No

Assay
Protease inhibition
SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]Zablotna E et al. (2006) Biochem Biophys Res Commun 340:823-8

References
Zablotna E, Kret A, Jaskiewicz A, Olma A, Leplawy MT, Rolka K (2006) Introduction of alpha-hydroxymethyamino acid residues in substrate specificity P1 position of trypsin inhibitor SFTI-1 from sunflower seeds retains its activity. Biochem Biophys Res Commun 340:823-8

Cross-references
Nucleic acids
Structure
Links

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