cMCoTI-fxL5(1889) Protein Card

General Information
Name cMCoTI-fxL5
Sequence GGVCPKILKKCRRDSDCPGACICRATRFCGSGSD
Class Squash trypsin inhibitor
Average Mass 3537.10
Monoisotopic Mass 3534.6
m/z M+H 3537.1
ProteinType Grafted
Parent MCoTI-II
Organism Synthetic
Notes
Cyclic Yes

Assay
Protease inhibition
Inhibitory activity of cMCoTI-fxL5 against a panel of serine proteases [...]Liu W et al. (2021) J Am Chem Soc 143:18481-18489

References
Liu W, de Veer SJ, Huang YH, Sengoku T, Okada C, Ogata K, Zdenek CN, Fry BG, Swedberg JE, Passioura T, Craik DJ, Suga H. (2021) An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human beta-Factor XIIa in a Cyclotide Scaffold J Am Chem Soc 143:18481-18489

Cross-references
Nucleic acids
Structure
Links

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