alca 1(1876) Protein Card

General Information
Name alca 1
Sequence GVIPCGESCVFIPCISAAIGCSCKNKVCYRD
Class Cyclotide
Technique MS
Average Mass 3212.80
Monoisotopic Mass 3210.43
m/z M+H 3212.8
ProteinType Wild type
Parent
Organism Allexis cauliflora
Notes
Cyclic Yes

Assay
Protease inhibition
alac 1 and alac 2 have micromolar inhibitory activity for human prolyl oligopeptidase (POP). [...]Gattringer J et al. (2021) Front Pharmacol 12:707596-0

References
Gattringer J, Ndogo OE, Retzl B, Ebermann C, Gruber CW, Hellinger R. (2021) Cyclotides Isolated From Violet Plants of Cameroon Are Inhibitors of Human Prolyl Oligopeptidase. Front Pharmacol 12:707596-0

Cross-references
Nucleic acids
Structure
Links

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