(20) Assay Card

General Information
Summary Showed that kalata B1 and B6 would bind selectively to bacterial membranes.
Condition Membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance
Result We also determined the affinity of two kalata peptides to each phospholipid membrane and demonstrated a higher affinity for the DMPE-containing membranes. These results indicate that the kalata peptides would bind selectively to bacterial membranes.
AssayType Membrane Binding Assay

References
Kamimori H, Hall K, Craik DJ, Aguilar MI (2005) Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. Anal Biochem 337:149-53

Cross-references
Proteins Assayed kalata B1
kalata B6