Protein List

Found 16 entries.


ID Name Class Organism Assay Summary
552 psyle A Cyclotide Psychotria leptothyrsa Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]
554 psyle C Cyclotide Psychotria leptothyrsa Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]
556 psyle E Cyclotide Psychotria leptothyrsa Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]
Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
239 ([Lys(Ac)]2[Arg(CHD)])cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
237 [Lys(Ac)]2cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
238 [Arg(CHD)]cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
236 [Glu(Me)]cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
355 vibi D Cyclotide Viola biflora vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
356 vibi E Cyclotide Viola biflora vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
359 vibi H Cyclotide Viola biflora
Psychotria leptothyrsa
vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
37 kalata S Cyclotide Viola odorata
Oldenlandia affinis
Viola tricolor
Viola arvensis
Viola baoshanensis
Viola yedoensis
Viola biflora
Viola philippica
Viola ignobilis
All three cyclotides, varv A, varv F, and cycloviolacin O2, exhibited strong cytotoxic activities, which varied in a dose-dependent manner. [...]
Vitri A, varv A and varv E shown to possess cytotoxic activity in cancer cells. [...]
21 cycloviolacin O2 Cyclotide Viola odorata
Viola biflora
Viola philippica
Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
Studies using calcein assay and HeLa cells showed that at 10 uM, the increase in calcein leakage is very rapid. [...]
Cell viability and morphology studies on the human lymphoma cell line U-937 GTB showed that cells exposed to cycloviolacin O2 displayed disintegrated cell membranes within 5 min. [...]
All three cyclotides, varv A, varv F, and cycloviolacin O2, exhibited strong cytotoxic activities, which varied in a dose-dependent manner. [...]
Glutamic acid mutant had reduced activity [...]
64 varv peptide F Cyclotide Viola tricolor
Viola arvensis
All three cyclotides, varv A, varv F, and cycloviolacin O2, exhibited strong cytotoxic activities, which varied in a dose-dependent manner. [...]
38 cycloviolacin O12 Cyclotide Viola tricolor
Viola arvensis
Viola baoshanensis
Viola yedoensis
Viola tianshanica
Viola abyssinica
Viola philippica
Vitri A, varv A and varv E shown to possess cytotoxic activity in cancer cells. [...]
36 vitri A Cyclotide Viola tricolor
Viola biflora
Psychotria leptothyrsa
Vitri A, varv A and varv E shown to possess cytotoxic activity in cancer cells. [...]
358 vibi G Cyclotide Viola tricolor
Viola biflora
Psychotria leptothyrsa
vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]