ID
Name
Class
Organism
Assay Summary
1
kalata B1
Cyclotide
Viola odorata Oldenlandia affinis Viola tricolor Viola baoshanensis Viola yedoensis Viola philippica
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...] Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
5
palicourein
Cyclotide
Palicourea condensata
Palicourein shown to have anti-HIV properties. [...]
7
tricyclon A
Cyclotide
Viola tricolor Viola arvensis
Kalata B8 showed anti-HIV and cytotoxic activity. Tricyclon A did not show anti-HIV or cytotoxic activity. [...]
8
circulin A
Cyclotide
Chassalia parvifolia Chassalia chartacea
Circulin A and B shown to possess antiviral cytoprotective activity. [...]
15
kalata b1-2
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
16
kalata b1-3
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
18
kalata b1-5
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
19
kalata b1-6a
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
20
kalata b1-6b
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
37
kalata S
Cyclotide
Viola odorata Oldenlandia affinis Viola tricolor Viola arvensis Viola baoshanensis Viola yedoensis Viola biflora Viola philippica Viola ignobilis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
38
cycloviolacin O12
Cyclotide
Viola tricolor Viola arvensis Viola baoshanensis Viola yedoensis Viola tianshanica Viola abyssinica Viola philippica
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
45
circulin B
Cyclotide
Chassalia parvifolia
Circulin A and B shown to possess antiviral cytoprotective activity. [...]
48
circulin C
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
49
circulin D
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
50
circulin E
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
51
circulin F
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
67
cycloviolin A
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
68
cycloviolin B
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
69
cycloviolin C
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
70
cycloviolin D
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
86
vhl-1
Cyclotide
Viola hederacea
vhl-1 inhibited HIV infection with EC50 of 0.87 uM [...]
168
kalata B8
Cyclotide
Oldenlandia affinis
Kalata B8 showed anti-HIV and cytotoxic activity. Tricyclon A did not show anti-HIV or cytotoxic activity. [...]
170
cycloviolacin O13
Cyclotide
Viola odorata
Cycloviolacin O13, O14 and O24 inhibited the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells with antiviral cytoprotective concentrations (EC50) of 320, 440, and 308 nM, while the cytotoxic concentration (IC50) was 6.4, 4.8, and 6.2 uM, respectively [...]
174
cycloviolacin O14
Cyclotide
Viola odorata
Cycloviolacin O13, O14 and O24 inhibited the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells with antiviral cytoprotective concentrations (EC50) of 320, 440, and 308 nM, while the cytotoxic concentration (IC50) was 6.4, 4.8, and 6.2 uM, respectively [...]
184
cycloviolacin O24
Cyclotide
Viola odorata
Cycloviolacin O13, O14 and O24 inhibited the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells with antiviral cytoprotective concentrations (EC50) of 320, 440, and 308 nM, while the cytotoxic concentration (IC50) was 6.4, 4.8, and 6.2 uM, respectively [...]
347
cycloviolacin Y1
Cyclotide
Viola yedoensis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
350
cycloviolacin Y4
Cyclotide
Viola yedoensis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
351
cycloviolacin Y5
Cyclotide
Viola baoshanensis Viola yedoensis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]