Welcome

Bibliography

Links

About us

References

Nucleic acids

Search

Primer Match

Proteins

Classes

Cyclotides

BBI-like TI

Bacterial

Orbitides

Cyclised linear

Mushroom

Primate

Sunflower cyclic

Squash TI

Search

Fingerprint Search

Loop Search

Tools

Cyclotide Collier de Perles

Sequence Diversity Wheel

Digest Peptide

Synthetic analogues

Cyclotide loop view

CyPred: sequence-based prediction of cyclic proteins

Plant Species devoid of Cyclotides

Structures

Search

Tools

Termini Distance Distributions

Termini proximity

Cyclisation Energy

CycloMod

Assays

Assays

Alpha Plot

Cyclic Seqplot

Bibliography

Contents

• List of Figures
• Introduction
  • The Cyclotides
    • Discovery and Initial Characterisation
    • Nomenclature and Sequence Conservation
    • Structural Characteristics of the cyclotides
    • Biosynthesis
    • Natural Activity of the cyclotides
    • Cyclotide Evolution
    • Summary
  • SFTI
    • Bowman-Birk Inhibitors and the Discovery of SFTI-1
    • Sequence and Structure
    • Biosynthesis
    • Evolution and Distribution
    • Summary
  • Other Cyclic Peptides
    • Knottins and Cyclic trypsin inhibitors from Cucurbitaceae
    • Cyclic Bacteriocins
    • Sex pilus subunits
    • -defensins
  • Summary and Common Themes
  
  
• References

CyBase is managed at the Institute of Molecular Bioscience IMB, Brisbane, Australia.

The database and computational tools found on this website may be used for academic research only, provided that it is referred to CyBase, the database of cyclic proteins (http://www.cybase.org.au). For any other use please contact David Craik (d.craik@imb.uq.edu.au).

Contacts:
David Craik
Conan Wang
Quentin Kaas

Last updated: Monday 25 January 2021