Protein List

Found 65 entries.


ID Name Class Organism Assay Summary
343 MCoTI-II[K10F] Squash trypsin inhibitor Synthetic Synthetic MCoTI-I and MCoTI-II are both extremely potent trypsin inhibitors. [K10R] mutant has essentially wild-type activity against trypsin, whilst [K10F] and [K10Q] mutants are less active. [K10F] is the only mutant to show significant activity against chymotrypsin in this assay. [...]
342 MCoTI-II[K10Q] Squash trypsin inhibitor Synthetic Synthetic MCoTI-I and MCoTI-II are both extremely potent trypsin inhibitors. [K10R] mutant has essentially wild-type activity against trypsin, whilst [K10F] and [K10Q] mutants are less active. [K10F] is the only mutant to show significant activity against chymotrypsin in this assay. [...]
341 MCoTI-II[K10R] Squash trypsin inhibitor Synthetic Synthetic MCoTI-I and MCoTI-II are both extremely potent trypsin inhibitors. [K10R] mutant has essentially wild-type activity against trypsin, whilst [K10F] and [K10Q] mutants are less active. [K10F] is the only mutant to show significant activity against chymotrypsin in this assay. [...]
233 [AlaG10]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
232 [R14]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
231 [R13]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
230 [R10]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
229 [A14]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
228 [A13]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
227 [A10]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
226 oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
219 SFTI-3 BBI-like trypsin inhibitor Synthetic Matriptase inhibitory activity of SFTI-2 is 25-fold less potent than native, while SFTI-3 exhibits similar potency. [...]
218 SFTI-2 BBI-like trypsin inhibitor Synthetic Matriptase inhibitory activity of SFTI-2 is 25-fold less potent than native, while SFTI-3 exhibits similar potency. [...]
217 [Ser3,11]aSFTI-1 BBI-like trypsin inhibitor Synthetic Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]
216 Seleno aSFTI-1 BBI-like trypsin inhibitor Synthetic Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]
215 [D14A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
214 [P13A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
213 [F12A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
212 [I10A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
211 [P9A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
210 [P8A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
209 [I7A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
208 [S6A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
207 [K5A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
206 [T4A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
205 [R2A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
204 [G1A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
203 [HmSer5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
202 [(R)HmVal5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
201 [(S)HmVal5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
200 [(R,S)HmVal5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
199 [Ser5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
198 [Val5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
196 HEI-TOS BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
195 OSFPKI III BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
193 OSFPKI I BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
194 OSFPKI II BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
192 OSFEI II BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
191 OSFEI I BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
137 MCoTI-I Squash trypsin inhibitor Momordica cochinchinensis Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
112 PP-SFTI-13 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
111 PP-SFTI-12 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
110 PP-SFTI-11 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
109 PP-SFTI-10 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
108 PP-SFTI-9 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
107 PP-SFTI-8 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
106 PP-SFTI-7 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
105 PP-SFTI-6 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
104 PP-SFTI-5 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
103 PP-SFTI-4 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
102 PP-SFTI-3 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
101 PP-SFTI-2 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
100 [Nphe5]SFTI-1 BBI-like trypsin inhibitor Synthetic Chymotrypsin and trypsin Ka values determined for SFTI-1 analogues. [...]
99 [Nlys5]SFTI-1 BBI-like trypsin inhibitor Synthetic Chymotrypsin and trypsin Ka values determined for SFTI-1 analogues. [...]
98 [ABA3,11]SFTI-1[1,14] BBI-like trypsin inhibitor Synthetic SFTI-1 analogues assayed for trypsin inhibitory activity. [...]
97 [ABA3,11]SFTI-1[6,5] BBI-like trypsin inhibitor Synthetic SFTI-1 analogues assayed for trypsin inhibitory activity. [...]
96 BiKF BBI-like trypsin inhibitor Synthetic Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity. [...]
95 BiKK BBI-like trypsin inhibitor Synthetic Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity. [...]
93 [ABA3,11]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 analogues assayed for trypsin inhibitory activity. [...]
SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity. [...]
81 SFTI-1 BBI-like trypsin inhibitor Helianthus annus
Helianthus exilis
Helianthus tuberosus		 Both SFTI-1 and acyclic SFTI-1 are potent inhibitors of bovine beta trypsin [...]
SFTI-1 was found to have nano-molar inhibitory effect against matriptase and trypsin. [...]
SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity. [...]
SFTI-1 immobilised on gold and interaction with trypsin investigated. [...]
Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity. [...]
Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
Matriptase inhibitory activity of SFTI-2 is 25-fold less potent than native, while SFTI-3 exhibits similar potency. [...]
83 SFTI-1(6,5) BBI-like trypsin inhibitor Synthetic SFTI-1(6,5) shown to have trypsin inhibitory activity and is cyclised after incubation with trypsin. [...]
82 N-SFTI-1-C BBI-like trypsin inhibitor Synthetic Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]
SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
Chymotrypsin and trypsin Ka values determined for SFTI-1 analogues. [...]
SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity. [...]
Both SFTI-1 and acyclic SFTI-1 are potent inhibitors of bovine beta trypsin [...]
4 kalata B2 Cyclotide Oldenlandia affinis Kalata B1 and B2 were found to have no trypsin or chymotrypsin inhibitory activity. [...]
3 MCoTI-II Squash trypsin inhibitor Momordica cochinchinensis Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
1 kalata B1 Cyclotide Viola odorata
Oldenlandia affinis
Viola tricolor
Viola baoshanensis
Viola yedoensis
Viola philippica
Viola sumatrana Miq		 Kalata B1 and B2 were found to have no trypsin or chymotrypsin inhibitory activity. [...]