Protein List

Found 65 entries.


ID Name Class Organism Assay Summary
343 MCoTI-II[K10F] Squash trypsin inhibitor Synthetic Synthetic MCoTI-I and MCoTI-II are both extremely potent trypsin inhibitors. [K10R] mutant has essentially wild-type activity against trypsin, whilst [K10F] and [K10Q] mutants are less active. [K10F] is the only mutant to show significant activity against chymotrypsin in this assay. [...]
342 MCoTI-II[K10Q] Squash trypsin inhibitor Synthetic Synthetic MCoTI-I and MCoTI-II are both extremely potent trypsin inhibitors. [K10R] mutant has essentially wild-type activity against trypsin, whilst [K10F] and [K10Q] mutants are less active. [K10F] is the only mutant to show significant activity against chymotrypsin in this assay. [...]
341 MCoTI-II[K10R] Squash trypsin inhibitor Synthetic Synthetic MCoTI-I and MCoTI-II are both extremely potent trypsin inhibitors. [K10R] mutant has essentially wild-type activity against trypsin, whilst [K10F] and [K10Q] mutants are less active. [K10F] is the only mutant to show significant activity against chymotrypsin in this assay. [...]
233 [AlaG10]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
232 [R14]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
231 [R13]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
230 [R10]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
229 [A14]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
228 [A13]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
227 [A10]oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
226 oMCoTI-II Squash trypsin inhibitor Synthetic Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
219 SFTI-3 BBI-like trypsin inhibitor Synthetic Matriptase inhibitory activity of SFTI-2 is 25-fold less potent than native, while SFTI-3 exhibits similar potency. [...]
218 SFTI-2 BBI-like trypsin inhibitor Synthetic Matriptase inhibitory activity of SFTI-2 is 25-fold less potent than native, while SFTI-3 exhibits similar potency. [...]
217 [Ser3,11]aSFTI-1 BBI-like trypsin inhibitor Synthetic Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]
216 Seleno aSFTI-1 BBI-like trypsin inhibitor Synthetic Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]
215 [D14A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
214 [P13A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
213 [F12A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
212 [I10A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
211 [P9A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
210 [P8A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
209 [I7A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
208 [S6A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
207 [K5A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
206 [T4A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
205 [R2A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
204 [G1A]SFTI-1 BBI-like trypsin inhibitor Synthetic 12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
203 [HmSer5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
202 [(R)HmVal5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
201 [(S)HmVal5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
200 [(R,S)HmVal5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
199 [Ser5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
198 [Val5]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
196 HEI-TOS BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
195 OSFPKI III BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
193 OSFPKI I BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
194 OSFPKI II BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
192 OSFEI II BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
191 OSFEI I BBI-like trypsin inhibitor Synthetic SFTI based variants shown to have activity against Porcine pancreatic elastase and Proteinase K [...]
137 MCoTI-I Squash trypsin inhibitor Momordica cochinchinensis Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
112 PP-SFTI-13 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
111 PP-SFTI-12 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
110 PP-SFTI-11 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
109 PP-SFTI-10 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
108 PP-SFTI-9 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
107 PP-SFTI-8 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
106 PP-SFTI-7 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
105 PP-SFTI-6 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
104 PP-SFTI-5 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
103 PP-SFTI-4 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
102 PP-SFTI-3 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
101 PP-SFTI-2 BBI-like trypsin inhibitor Synthetic Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
100 [Nphe5]SFTI-1 BBI-like trypsin inhibitor Synthetic Chymotrypsin and trypsin Ka values determined for SFTI-1 analogues. [...]
99 [Nlys5]SFTI-1 BBI-like trypsin inhibitor Synthetic Chymotrypsin and trypsin Ka values determined for SFTI-1 analogues. [...]
98 [ABA3,11]SFTI-1[1,14] BBI-like trypsin inhibitor Synthetic SFTI-1 analogues assayed for trypsin inhibitory activity. [...]
97 [ABA3,11]SFTI-1[6,5] BBI-like trypsin inhibitor Synthetic SFTI-1 analogues assayed for trypsin inhibitory activity. [...]
96 BiKF BBI-like trypsin inhibitor Synthetic Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity. [...]
95 BiKK BBI-like trypsin inhibitor Synthetic Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity. [...]
93 [ABA3,11]SFTI-1 BBI-like trypsin inhibitor Synthetic SFTI-1 analogues assayed for trypsin inhibitory activity. [...]
SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity. [...]
81 SFTI-1 BBI-like trypsin inhibitor Helianthus annus
Helianthus exilis
Helianthus tuberosus		 Both SFTI-1 and acyclic SFTI-1 are potent inhibitors of bovine beta trypsin [...]
SFTI-1 was found to have nano-molar inhibitory effect against matriptase and trypsin. [...]
SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity. [...]
SFTI-1 immobilised on gold and interaction with trypsin investigated. [...]
Bifunctional analogues of SFTI-1 found to have trypsin and chymotrypsin inhibitory activity. [...]
Ki calculated for a range of SFTI-1 analogues against trypsin and chymotrypsin. [...]
12 SFTI alanine mutants were tested for inhibitory activity against bovine trypsin. K5A mutant shows the weakest activity. [...]
Matriptase inhibitory activity of SFTI-2 is 25-fold less potent than native, while SFTI-3 exhibits similar potency. [...]
83 SFTI-1(6,5) BBI-like trypsin inhibitor Synthetic SFTI-1(6,5) shown to have trypsin inhibitory activity and is cyclised after incubation with trypsin. [...]
82 N-SFTI-1-C BBI-like trypsin inhibitor Synthetic Disulfide bond is essenial for structure and function of acyclic SFTI-1. Seleno aSFTI-1 has 30% reduced inhibitory constant. [...]
SFTI-1 and analogues shown to inhibit Bovine beta-trypsin and Human leukocyte elastase [...]
Chymotrypsin and trypsin Ka values determined for SFTI-1 analogues. [...]
SFTI-1, an acyclic permutant and a [CYS-Abu]-cyclic mutant shown to possess potent trypsin inhibitory activity. [...]
Both SFTI-1 and acyclic SFTI-1 are potent inhibitors of bovine beta trypsin [...]
4 kalata B2 Cyclotide Oldenlandia affinis Kalata B1 and B2 were found to have no trypsin or chymotrypsin inhibitory activity. [...]
3 MCoTI-II Squash trypsin inhibitor Momordica cochinchinensis Open chain variants have reduced inhibitory activity against bovine trypsin compared to native cyclic proteins. [...]
1 kalata B1 Cyclotide Viola odorata
Oldenlandia affinis
Viola tricolor
Viola baoshanensis
Viola yedoensis
Viola philippica		 Kalata B1 and B2 were found to have no trypsin or chymotrypsin inhibitory activity. [...]