Protein List

Found 16 entries.


ID Name Class Organism Assay Summary
556 psyle E Cyclotide Psychotria leptothyrsa Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]
Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
554 psyle C Cyclotide Psychotria leptothyrsa Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]
552 psyle A Cyclotide Psychotria leptothyrsa Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]
359 vibi H Cyclotide Viola biflora
Psychotria leptothyrsa
vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
358 vibi G Cyclotide Viola tricolor
Viola biflora
Psychotria leptothyrsa
vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
356 vibi E Cyclotide Viola biflora vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
355 vibi D Cyclotide Viola biflora vibi D, E, G and H were analysed using fluorometric microculture cytotoxicity assay using a lymphoma cell line. The IC50 values ranged between 0.96 and 5.0 uM for vibi E, G and H, and vibi D was not cytotoxic at 30 uM. [...]
239 ([Lys(Ac)]2[Arg(CHD)])cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
238 [Arg(CHD)]cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
237 [Lys(Ac)]2cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
236 [Glu(Me)]cyO2 Cyclotide Synthetic Glutamic acid mutant had reduced activity [...]
64 varv peptide F Cyclotide Viola tricolor
Viola arvensis
All three cyclotides, varv A, varv F, and cycloviolacin O2, exhibited strong cytotoxic activities, which varied in a dose-dependent manner. [...]
38 cycloviolacin O12 Cyclotide Viola tricolor
Viola arvensis
Viola baoshanensis
Viola yedoensis
Viola tianshanica
Viola abyssinica
Viola philippica
Vitri A, varv A and varv E shown to possess cytotoxic activity in cancer cells. [...]
37 kalata S Cyclotide Viola odorata
Oldenlandia affinis
Viola tricolor
Viola arvensis
Viola baoshanensis
Viola yedoensis
Viola biflora
Viola philippica
Viola ignobilis
Vitri A, varv A and varv E shown to possess cytotoxic activity in cancer cells. [...]
All three cyclotides, varv A, varv F, and cycloviolacin O2, exhibited strong cytotoxic activities, which varied in a dose-dependent manner. [...]
36 vitri A Cyclotide Viola tricolor
Viola biflora
Psychotria leptothyrsa
Vitri A, varv A and varv E shown to possess cytotoxic activity in cancer cells. [...]
21 cycloviolacin O2 Cyclotide Viola odorata
Viola biflora
Viola philippica
Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]
Studies using calcein assay and HeLa cells showed that at 10 uM, the increase in calcein leakage is very rapid. [...]
Cell viability and morphology studies on the human lymphoma cell line U-937 GTB showed that cells exposed to cycloviolacin O2 displayed disintegrated cell membranes within 5 min. [...]
All three cyclotides, varv A, varv F, and cycloviolacin O2, exhibited strong cytotoxic activities, which varied in a dose-dependent manner. [...]
Glutamic acid mutant had reduced activity [...]