ID
Name
Class
Organism
Assay Summary
351
cycloviolacin Y5
Cyclotide
Viola baoshanensis Viola yedoensis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
350
cycloviolacin Y4
Cyclotide
Viola yedoensis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
347
cycloviolacin Y1
Cyclotide
Viola yedoensis
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
184
cycloviolacin O24
Cyclotide
Viola odorata
Cycloviolacin O13, O14 and O24 inhibited the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells with antiviral cytoprotective concentrations (EC50) of 320, 440, and 308 nM, while the cytotoxic concentration (IC50) was 6.4, 4.8, and 6.2 uM, respectively [...]
174
cycloviolacin O14
Cyclotide
Viola odorata
Cycloviolacin O13, O14 and O24 inhibited the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells with antiviral cytoprotective concentrations (EC50) of 320, 440, and 308 nM, while the cytotoxic concentration (IC50) was 6.4, 4.8, and 6.2 uM, respectively [...]
170
cycloviolacin O13
Cyclotide
Viola odorata Hybanthus enneaspermus Viola baoshanensis Viola uliginosa Viola arcuata Viola austrosinensis
Cycloviolacin O13, O14 and O24 inhibited the cytopathic effects of HIV-1 infection in cultured human T-lymphoblast (CEM-SS) cells with antiviral cytoprotective concentrations (EC50) of 320, 440, and 308 nM, while the cytotoxic concentration (IC50) was 6.4, 4.8, and 6.2 uM, respectively [...]
168
kalata B8
Cyclotide
Oldenlandia affinis Hybanthus enneaspermus
Kalata B8 showed anti-HIV and cytotoxic activity. Tricyclon A did not show anti-HIV or cytotoxic activity. [...]
86
vhl-1
Cyclotide
Viola hederacea
vhl-1 inhibited HIV infection with EC50 of 0.87 uM [...]
8
circulin A
Cyclotide
Chassalia parvifolia Chassalia chartacea
Circulin A and B shown to possess antiviral cytoprotective activity. [...]
7
tricyclon A
Cyclotide
Viola tricolor Viola arvensis
Kalata B8 showed anti-HIV and cytotoxic activity. Tricyclon A did not show anti-HIV or cytotoxic activity. [...]
5
palicourein
Cyclotide
Palicourea condensata
Palicourein shown to have anti-HIV properties. [...]
1
kalata B1
Cyclotide
Viola odorata Oldenlandia affinis Viola tricolor Hybanthus enneaspermus Viola baoshanensis Viola yedoensis Viola philippica Viola sumatrana Miq
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...] Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
70
cycloviolin D
Cyclotide
Leonia cymosa Viola uliginosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
69
cycloviolin C
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
68
cycloviolin B
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
67
cycloviolin A
Cyclotide
Leonia cymosa
Cycloviolins A-D shown to possess anti-HIV activity. [...]
51
circulin F
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
50
circulin E
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
49
circulin D
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
48
circulin C
Cyclotide
Chassalia parvifolia
Circulins C-F inhibited the cytopathic effects of in vitro HIV-1 infection. [...]
45
circulin B
Cyclotide
Chassalia parvifolia
Circulin A and B shown to possess antiviral cytoprotective activity. [...]
38
cycloviolacin O12
Cyclotide
Viola tricolor Viola arvensis Viola baoshanensis Viola yedoensis Viola tianshanica Viola abyssinica Viola philippica Viola arcuata
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
37
kalata S
Cyclotide
Viola odorata Oldenlandia affinis Viola tricolor Viola arvensis Viola baoshanensis Viola yedoensis Viola biflora Viola philippica Viola ignobilis Viola uliginosa Viola sumatrana Miq Viola arcuata
All cyclotides tested from V. yedoensis demonstrated anti-HIV activity, with cycloviolacin Y5 being the most potent. [...]
20
kalata b1-6b
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
19
kalata b1-6a
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
18
kalata b1-5
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
16
kalata b1-3
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]
15
kalata b1-2
Cyclotide
Synthetic
Anti-HIV activity shown for kalata B1 but not for acyclic permutants. [...]