Reference List

Found 267 entries.

Bobey,A.F., Pinto,M.E.F., Cilli,E.M., Lopes,N.P. and Bolzani,V.D.S.
A Cyclotide Isolated from Noisettia orchidiflora (Violaceae). Planta Med. (2018) 84: 947-952
Pinto,M.E.F., Najas,J.Z.G., Magalhães,L.G., Bobey,A.F., Mendonça,J.N., Lopes,N.P., Leme,F.M., Teixeira,S.P., Trovó,M., Andricopulo,A.D., Koehbach,J., Gruber,C.W., Cilli,E.M. and Bolzani,V.S.
Inhibition of Breast Cancer Cell Migration by Cyclotides Isolated from Pombalia calceolaria. J. Nat. Prod. (2018) 81: 1203-1208
Abdul Ghani H, Henriques ST, Huang YH, Swedberg JE, Schroeder CI, Craik DJ
Structural and functional characterisation of chimeric cyclotides from the Möbius and trypsin inhibitor subfamilies Biopolymers (2016) : 0-0
Attah,A.F., Hellinger,R., Sonibare,M.A., Moody,J.O., Arrowsmith,S., Wray,S. and Gruber,C.W.
Ethnobotanical survey of Rinorea dentata (Violaceae) used in South-Western Nigerian ethnomedicine and detection of cyclotides. J Ethnopharmacol (2016) 179: 83-91
Esmaeili,M.A., Abagheri-Mahabadi,N., Hashempour,H., Farhadpour,M., Gruber,C.W. and Ghassempour,A.
Viola plant cyclotide vigno 5 induces mitochondria-mediated apoptosis via cytochrome C release and caspases activation in cervical cancer cells. Fitoterapia (2016) 109: 162-168
Farhadpour,M., Hashempour,H., Talebpour,Z., A-Bagheri,N., Shushtarian,M.S., Gruber,C.W. and Ghassempour,A.
Microwave-assisted extraction of cyclotides from Viola ignobilis. Anal. Biochem. (2016) 497: 83-89
Gilding,E.K., Jackson,M.A., Poth,A.G., Henriques,S.T., Prentis,P.J., Mahatmanto,T. and Craik,D.J.
Gene coevolution and regulation lock cyclic plant defence peptides to their targets. New Phytol. (2016) 210: 717-730
Glantz,S.T., Carpenter,E.J., Melkonian,M., Gardner,K.H., Boyden,E.S., Wong,G.K. and Chow,B.Y.
Functional and topological diversity of LOV domain photoreceptors. Proc. Natl. Acad. Sci. U.S.A. (2016) 113: 0-51
Nguyen KN, Nguyen GK, Nguyen PQ, Ang KH, Dedon PC, Tam JP
Immunostimulating and Gram-negative-specific Antibacterial Cyclotides from the Butterfly Pea Clitoria ternatea. FEBS J (2016) doi:10.1111/febs.13720: 0-0
Serra,A., Hemu,X., Nguyen,G.K., Nguyen,N.T., Sze,S.K. and Tam,J.P.
A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides. Sci Rep (2016) 6: 23005-0
Thell K, Hellinger R, Sahin E, Michenthaler P, Gold-Binder M, Haider T, Kuttke M, Liutkevičiūtė Z, Göransson U, Gründemann C, Schabbauer G, Gruber CW
Oral activity of a nature-derived cyclic peptide for the treatment of multiple sclerosis Proc Natl Acad Sci USA (2016) 113: 3960-3965
Hellinger,R., Koehbach,J., Puigpinós,A., Clark,R.J., Tarragó,T., Giralt,E. and Gruber,C.W.
Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum. J. Nat. Prod. (2015) 78: 1073-1082
Hellinger,R., Koehbach,J., Soltis,D.E., Carpenter,E.J., Wong,G.K. and Gruber,C.W.
Peptidomics of Circular Cysteine-Rich Plant Peptides: Analysis of the Diversity of Cyclotides from Viola tricolor by Transcriptome and Proteome Mining. J. Proteome Res. (2015) 14: 4851-4862
Pinto,M.E., Batista,J.M. Jr., Koehbach,J., Gaur,P., Sharma,A., Nakabashi,M., Cilli,E.M., Giesel,G.M., Verli,H., Gruber,C.W., Blanch,E.W., Tavares,J.F., da Silva,M.S., Garcia,C.R. and Bolzani,V.S.
Ribifolin, an orbitide from Jatropha ribifolia, and its potential antimalarial activity. J. Nat. Prod. (2015) 78: 374-380
Ravipati,A.S., Henriques,S.T., Poth,A.G., Kaas,Q., Wang,C.K., Colgrave,M.L. and Craik,D.J.
Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae. ACS Chem. Biol. (2015) 10: 2491-2500
Altei,W.F., Picchi,D.G., Abissi,B.M., Giesel,G.M., Flausino,O. Jr., Reboud-Ravaux,M., Verli,H., Crusca,E. Jr., Silveira,E.R., Cilli,E.M. and Bolzani,V.S.
Jatrophidin I, a cyclic peptide from Brazilian Jatropha curcas L.: isolation, characterization, conformational studies and biological activity. Phytochemistry (2014) 107: 91-96
Mu,F., Masuda,Y., Zendo,T., Ono,H., Kitagawa,H., Ito,H., Nakayama,J. and Sonomoto,K.
Biological function of a DUF95 superfamily protein involved in the biosynthesis of a circular bacteriocin, leucocyclicin Q. J. Biosci. Bioeng. (2014) 117: 158-164
Hashempour,H., Koehbach,J., Daly,N.L., Ghassempour,A. and Gruber,C.W.
Characterizing circular peptides in mixtures: sequence fragment assembly of cyclotides from a violet plant by MALDI-TOF/TOF mass spectrometry. Amino Acids (2013) 44: 581-595
Ji,Y., Majumder,S., Millard,M., Borra,R., Bi,T., Elnagar,A.Y., Neamati,N., Shekhtman,A. and Camarero,J.A.
In vivo activation of the p53 tumor suppressor pathway by an engineered cyclotide. J. Am. Chem. Soc. (2013) 135: 11623-11633
Koehbach,J., Attah,A.F., Berger,A., Hellinger,R., Kutchan,T.M., Carpenter,E.J., Rolf,M., Sonibare,M.A., Moody,J.O., Wong,G.K., Dessein,S., Greger,H. and Gruber,C.W.
Cyclotide discovery in Gentianales revisited-identification and characterization of cyclic cystine-knot peptides and their phylogenetic distribution in Rubiaceae plants. Biopolymers (2013) 100: 438-452
Koehbach,J., O Brien,M., Muttenthaler,M., Miazzo,M., Akcan,M., Elliott,A.G., Daly,N.L., Harvey,P.J., Arrowsmith,S., Gunasekera,S., Smith,T.J., Wray,S., Goransson,U., Dawson,P.E., Craik,D.J., Freissmuth,M. and Gruber,C.W.
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design. Proc. Natl. Acad. Sci. U.S.A (2013) 110: 21183-21188
Nguyen,G.K., Lian,Y., Pang,E.W., Nguyen,P.Q., Tran,T.D. and Tam,J.P.
Discovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants. J. Biol. Chem. (2013) 288: 3370-3380
Zarrabi,M., Dalirfardouei,R., Sepehrizade,Z. and Kermanshahi,R.K.
Comparison of the antimicrobial effects of semipurified cyclotides from Iranian Viola odorata against some of plant and human pathogenic bacteria. J. Appl. Microbiol. (2013) 115: 367-375
Aboye,T.L., Ha,H., Majumder,S., Christ,F., Debyser,Z., Shekhtman,A., Neamati,N. and Camarero,J.A.
Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity. J. Med. Chem. (2012) 55: 10729-10734
Eliasen,R., Daly,N.L., Wulff,B.S., Andresen,T.L., Conde-Frieboes,K.W. and Craik,D.J.
Design, synthesis, structural and functional characterization of novel melanocortin agonists based on the cyclotide kalata B1. J. Biol. Chem. (2012) 287: 40493-40501
Mylne,J.S., Chan,L.Y., Chanson,A.H., Daly,N.L., Schaefer,H., Bailey,T.L., Nguyencong,P., Cascales,L. and Craik,D.J.
Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase-mediated biosynthesis. Plant Cell (2012) 24: 2765-2778
Nguyen,G.K., Lim,W.H., Nguyen,P.Q. and Tam,J.P.
Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities. J. Biol. Chem. (2012) 287: 17598-17607
Pinto,M.F., Fensterseifer,I.C., Migliolo,L., Sousa,D.A., de Capdville,G., Arboleda-Valencia,J.W., Colgrave,M.L., Craik,D.J., Magalhães,B.S., Dias,S.C. and Franco,O.L.
Identification and structural characterization of novel cyclotide with activity against an insect pest of sugar cane. J. Biol. Chem. (2012) 287: 134-147
Poth,A.G., Mylne,J.S., Grassl,J., Lyons,R.E., Millar,A.H., Colgrave,M.L. and Craik,D.J.
Cyclotides associate with leaf vasculature and are the products of a novel precursor in petunia (Solanaceae). J. Biol. Chem. (2012) 287: 27033-27046
Tischler,M., Nasu,D., Empting,M., Schmelz,S., Heinz,D.W., Rottmann,P., Kolmar,H., Buntkowsky,G., Tietze,D. and Avrutina,O.
Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations. Angew. Chem. Int. Ed. Engl. (2012) 51: 3708-3712
Wong,C.T., Rowlands,D.K., Wong,C.H., Lo,T.W., Nguyen,G.K., Li,H.Y. and Tam,J.P.
Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment. Angew. Chem. Int. Ed. Engl. (2012) 51: 5620-5624
Borrero J, Brede DA, Skaugen M, Diep DB, Herranz C, Nes IF, Cintas LM, Hernández PE
Characterization of garvicin ML, a novel circular bacteriocin produced by Lactococcus garvieae DCC43, isolated from mallard ducks (Anas platyrhynchos). Appl Environ Microbiol (2011) 77: 369-373
Burman,R., Strömstedt,A.A., Malmsten,M. and Göransson,U.
Cyclotide-membrane interactions: defining factors of membrane binding, depletion and disruption. Biochim. Biophys. Acta (2011) 1808: 2665-2673
Cascales,L., Henriques,S.T., Kerr,M.C., Huang,Y.H., Sweet,M.J., Daly,N.L. and Craik,D.J.
Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides. J. Biol. Chem. (2011) 286: 36932-36943
Chan,L.Y., Gunasekera,S., Henriques,S.T., Worth,N.F., Le,S.J., Clark,R.J., Campbell,J.H., Craik,D.J. and Daly,N.L.
Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds. Blood (2011) 118: 6709-6717
Condie JA, Nowak G, Reed DW, Balsevich JJ, Reaney MJ, Arnison PG, Covello PS
The biosynthesis of Caryophyllaceae-like cyclic peptides in Saponaria vaccaria L. from DNA-encoded precursors. Plant J (2011) 67: 682-90
Contreras,J., Elnagar,A.Y., Hamm-Alvarez,S.F. and Camarero,J.A.
Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways. J Control Release (2011) 155: 134-143
Hashempour,H., Ghassempour,A., Daly,N.L., Spengler,B. and Römpp,A.
Analysis of cyclotides in Viola ignobilis by Nano liquid chromatography fourier transform mass spectrometry. Protein Pept. Lett. (2011) 18: 747-752
He,W., Chan,L.Y., Zeng,G., Daly,N.L., Craik,D.J. and Tan,N.
Isolation and characterization of cytotoxic cyclotides from Viola philippica. Peptides (2011) 32: 1719-1723
Masuda,Y., Ono,H., Kitagawa,H., Ito,H., Mu,F., Sawa,N., Zendo,T. and Sonomoto,K.
Identification and characterization of leucocyclicin Q, a novel cyclic bacteriocin produced by Leuconostoc mesenteroides TK41401. Appl. Environ. Microbiol. (2011) 77: 8164-8170
Mylne JS, Colgrave ML, Daly NL, Chanson AH, Elliott AG, McCallum EJ, Jones A, Craik DJ.
Albumins and their processing machinery are hijacked for cyclic peptides in sunflower. Nat Chem Biol (2011) 7: 257-259
Nguyen,G.K., Zhang,S., Nguyen,N.T., Nguyen,P.Q., Chiu,M.S., Hardjojo,A. and Tam,J.P.
Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family. J. Biol. Chem. (2011) 286: 24275-24287
Nguyen,G.K., Zhang,S., Wang,W., Wong,C.T., Nguyen,N.T. and Tam,J.P.
Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry. J. Biol. Chem. (2011) 286: 44833-44844
Ovesen,R.G., Nielsen,J. and Hansen,H.C.
Biomedicine in the environment: sorption of the cyclotide kalata B2 to montmorillonite, goethite, and humic acid. Environ. Toxicol. Chem. (2011) 30: 1785-1792
Poth AG, Colgrave ML, Lyons RE, Daly NL, Craik DJ
Discovery of an unusual biosynthetic origin for circular proteins in legumes Proc Natl Acad Sci USA (2011) 108: 10127-10132
Poth AG, Colgrave ML, Philip R, Kerenga B, Daly NL, Anderson MA, Craik DJ
Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins. ACS Chem Biol (2011) 6: 345-355
Sando,L., Henriques,S.T., Foley,F., Simonsen,S.M., Daly,N.L., Hall,K.N., Gustafson,K.R., Aguilar,M.I. and Craik,D.J.
A Synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor. Chembiochem (2011) 12: 2456-2462
Wang,C.K., Clark,R.J., Harvey,P.J., Rosengren,K.J., Cemazar,M. and Craik,D.J.
The role of conserved Glu residue on cyclotide stability and activity: a structural and functional study of kalata B12, a naturally occurring Glu to Asp mutant. Biochemistry (2011) 50: 4077-4086
Wong CT, Taichi M, Nishio H, Nishiuchi Y, Tam JP
Optimal Oxidative Folding of the Novel Antimicrobial Cyclotide from Hedyotis biflora Requires High Alcohol Concentrations. Biochemistry (2011) [ahead]: 0-0
Yeshak MY, Burman R, Asres K, Göransson U
Cyclotides from an Extreme Habitat: Characterization of Cyclic Peptides from Viola abyssinica of the Ethiopian Highlands J Nat Prod (2011) [ahead]: 0-0
Yuan,C., Chen,L., Meehan,E.J., Daly,N., Craik,D.J., Huang,M. and Ngo,J.C.
Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1. BMC Struct. Biol. (2011) 11: 30-0
Zenoni,S., D Agostino,N., Tornielli,G.B., Quattrocchio,F., Chiusano,M.L., Koes,R., Zethof,J., Guzzo,F., Delledonne,M., Frusciante,L., Gerats,T. and Pezzotti,M.
Revealing impaired pathways in the an11 mutant by high-throughput characterization of Petunia axillaris and Petunia inflata transcriptomes. Plant J. (2011) 68: 11-27
Breuillin,F., Schramm,J., Hajirezaei,M., Ahkami,A., Favre,P., Druege,U., Hause,B., Bucher,M., Kretzschmar,T., Bossolini,E., Kuhlemeier,C., Martinoia,E., Franken,P., Scholz,U. and Reinhardt,D.
Phosphate systemically inhibits development of arbuscular mycorrhiza in Petunia hybrida and represses genes involved in mycorrhizal functioning. Plant J. (2010) 64: 1002-1017
Burman R, Gruber CW, Rizzardi K, Herrmann A, Craik DJ, Gupta MP, Göransson U
Cyclotide proteins and precursors from the genus Gloeospermum: filling a blank spot in the cyclotide map of Violaceae. Phytochemistry (2010) 71: 13-20
Colgrave ML, Poth AG, Kaas Q, Craik DJ
A new ‘era’ for cyclotide sequencing. Biopolymers: Peptide Science (2010) 94: 592-601
Daly NL, Chen B, Nguyencong P, Craik DJ
Structure and Activity of the Leaf-Specific Cyclotide vhl-2. Australian Journal of Chemistry (2010) 63: 771-778
Gerlach SL, Burman R, Bohlin L, Mondal D, Göransson U
Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa J Nat Prod (2010) 73: 1207-1213
Gerlach SL, Rathinakumar R, Chakravarty G, Göransson U, Wimley WC, Darwin SP, Mondal D
Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa. Biopolymers (2010) 94: 617-625
Mylne JS, Wang CK, van der Weerden NL, Craik DJ
Cyclotides are a component of the innate defense of Oldenlandia affinis. Biopolymers (2010) 94: 635-646
Plan MR, Rosengren KJ, Sando L, Daly NL, Craik DJ
Structural and biochemical characteristics of the cyclotide Kalata B5 from Oldenlandia affinis. Biopolymers (2010) 94: 647-658
Puttamadappa,S.S., Jagadish,K., Shekhtman,A. and Camarero,J.A.
Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin. Angew. Chem. Int. Ed. Engl. (2010) 49: 7030-7034
Qin Q, McCallum EJ, Kaas Q, Suda J, Saska I, Craik DJ, Mylne JS.
Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis. BMC Genomics (2010) 11: 111-0
Stegemann C, Tsvetkova EV, Aleshina GM, Lehrer RI, Kokryakov VN, Hoffmann R.
De novo sequencing of two new cyclic theta-defensins from baboon (Papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry. Rapid Commun Mass Spectrom (2010) 24: 599-604
Tang J, Wang CK, Pan X, Yan H, Zeng G, Xu W, He W, Daly NL, Craik DJ, Tan N
Isolation and characterization of cytotoxic cyclotides from Viola tricolor. Peptides (2010) 31: 1434-1440
Xiang B, Du GH, Wang XC, Zhang SX, Qin XY, Kong JQ, Cheng KD, Li YJ, Wang W
Elucidating the structure of two cyclotides of Viola tianshanica maxim by MALDI TOF/TOF MS analysis Yao Xue Xue Bao (2010) 45: 1402-1409
Göransson,U., Herrmann,A., Burman,R., Haugaard-Jönsson,L.M. and Rosengren,K.J.
The conserved glu in the cyclotide cycloviolacin O2 has a key structural role. Chembiochem (2009) 10: 2354-2360
Martin-Visscher,L.A., Gong,X., Duszyk,M. and Vederas,J.C.
The three-dimensional structure of carnocyclin A reveals that many circular bacteriocins share a common structural motif. J. Biol. Chem. (2009) 284: 28674-28681
Sawa N, Zendo T, Kiyofuji J, Fujita K, Himeno K, Nakayama J, Sonomoto K
Identification and characterization of lactocyclicin Q, a novel cyclic bacteriocin produced by Lactococcus sp. strain QU 12. Appl Environ Microbiol (2009) 75: 1552-1558
Trabi M, Mylne JS, Bharathi R, Sando L and Craik DJ
Circular proteins from Melicytus (Violaceae) refine the conserved protein and gene architecture of cyclotides. Org Biomol Chem (2009) 7: 2378-2388
Wang CK, Colgrave ML, Ireland DC, Kaas Q, Craik DJ
Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes. Biophys J. (2009) 97: 1471-1481
Wang CK, Hu SH, Martin JL, Sjögren T, Hajdu J, Bohlin L, Claeson P, Göransson U, Rosengren KJ, Tang J, Tan NH, Craik DJ
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold. J Biol Chem (2009) 284: 10672-10683
Zhang J, Liao B, Craik DJ, Li J-T, Hu M, Shu W
Identification of two suites of cyclotide precursor genes from metallophyte Viola baoshanensis: cDNA sequence variation, alternative RNA splicing and potential cyclotide diversity Gene (2009) 431: 23-32
Barbeta BL, Marshall AT, Gillon AD, Craik DJ, Anderson MA
Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae Proc Natl Acad Sci U S A (2008) 105: 1221-1225
Brueckner F, Cramer P
Structural Basis of Transcription Inhibition by Alpha-Amanitin and Implications for RNA Polymerase II Translocation. Nat Struct Mol Biol (2008) 15: 811-818
Cemazar M, Joshi A, Daly NL, Mark AE, Craik DJ
The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein. Structure (2008) 16: 842-851
Colgrave ML, Kotze AC, Huang YH, O'Grady J, Simonsen SM, Craik DJ.
Cyclotides: natural, circular plant peptides that possess significant activity against gastrointestinal nematode parasites of sheep. Biochemistry (2008) 47: 5581-5589
Colgrave ML, Kotze AC, Ireland DC, Wang CK, Craik DJ
The anthelmintic activity of the cyclotides: natural variants with enhanced activity Chembiochem (2008) 9: 1939-1945
Garcia AE, Osapay G, Tran PA, Yuan J, Selsted ME
Isolation, synthesis, and antimicrobial activities of naturally occurring theta-defensin isoforms from baboon leukocytes. Infect Immun (2008) 76: 5853-5891
Gruber CW, Elliott AG, Ireland DC, Delprete PG, Dessein S, Göransson U, Trabi M, Wang CK, Kinghorn AB, Robbrecht E, Craik DJ
Distribution and evolution of circular miniproteins in flowering plants. Plant Cell (2008) 20: 2471-2483
Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, Goransson U
The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity Phytochemistry (2008) 69: 939-952
Ireland DC, Wang CK, Wilson JA, Gustafson KR, Craik DJ
Cyclotides as natural anti-HIV agents Biopolymers (2008) 90: 51-60
Martin-Visscher,L.A., van Belkum,M.J., Garneau-Tsodikova,S., Whittal,R.M., Zheng,J., McMullen,L.M. and Vederas,J.C.
Isolation and characterization of carnocyclin a, a novel circular bacteriocin produced by Carnobacterium maltaromaticum UAL307. Appl. Environ. Microbiol. (2008) 74: 4756-4763
Mozoruk J, Hunnicutt LE, Hunter WB, Bausher MG
CsV03-3 is a member of a novel gene family from citrus that encodes a protein with DNA binding activity and whose expression is responsive to defense signals and abiotic stress. J Plant Physiol (2008) 165: 531-543
Plan MR, Saska I, Cagauan AG, Craik DJ
Backbone cyclised peptides from plants show molluscicidal activity against the rice pest Pomacea canaliculata (golden apple snail) J Agric Food Chem (2008) 56: 5237-5241
Shenkarev ZO, Nadezhdin KD, Lyukmanova EN, Sobol VA, Skjeldal L, Arseniev AS
Divalent cation coordination and mode of membrane interaction in cyclotides: NMR spatial structure of ternary complex Kalata B7/Mn2+/DPC micelle. J Inorg Biochem (2008) 102: 1246-1256
Shenkarev ZO, Nadezhdin KD, Sobol VA, Sobol AG, Skjeldal L, Arseniev AS.
Conformation and mode of membrane interaction in cyclotides. Spatial structure of kalata B1 bound to a dodecylphosphocholine micelle. FEBS J (2008) 273: 2658-2672
Simonsen SM, Sando L, Rosengren KJ, Wang CK, Colgrave ML, Daly NL, Craik DJ
Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity J Biol Chem (2008) 283: 9805-9813
Hallen HE, Luo H, Scott-Craig JS, Walton JD
Gene family encoding the major toxins of lethal Amanita mushrooms Proc Natl Acad Sci U S A (2007) 104: 19097-19101
Jiang S, Li P, Lee SL, Lin CY, Long YQ, Johnson MD, Dickson RB, Roller PP
Design and synthesis of redox stable analogues of sunflower trypsin inhibitors (SFTI-1) on solid support, potent inhibitors of matriptase. Org Lett (2007) 9: 9-12
Plan MR, Goransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ
The Cyclotide Fingerprint in Oldenlandia affinis: Elucidation of Chemically Modified, Linear and Novel Macrocyclic Peptides Chembiochem (2007) 8: 1001-1011
Seydel P, Gruber CW, Craik DJ, Dörnenburg H
Formation of cyclotides and variations in cyclotide expression in Oldenlandia affinis suspension cultures. Appl Microbiol Biotechnol. (2007) 77: 275-284
Shimamura,K., Ishimizu,T., Nishimura,K., Matsubara,K., Kodama,H., Watanabe,H., Hase,S. and Ando,T.
Analysis of expressed sequence tags from petunia flowers Plant Sci. (2007) 173: 495-500
Svangard E, Burman R, Gunasekera S, Lovborg H, Gullbo J, Goransson U
Mechanism of action of cytotoxic cyclotides: cycloviolacin O2 disrupts lipid membranes. J Nat Prod (2007) 70: 643-647
Thongyoo P, Jaulent AM, Tate EW, Leatherbarrow, RJ
Immobilized protease-assisted sysnthesis of engineered cysteine-knot microproteins Chembiochem (2007) 8: 1107-1109
Wang CK, Colgrave ML, Gustafson KR, Ireland DC, Göransson U, Craik DJ
Anti-HIV Cyclotides from the CHinese Medicinal Herb Viola yedoensis J Nat Prod (2007) 71: 47-52
Wirawan RE, Swanson KM, Kleffmann T, Jack RW, Tagg JR
Uberolysin: a novel cyclic bacteriocin produced by Streptococcus uberis. Microbiology (2007) 153: 1619-30
Cemazar M, Daly NL, Häggblad S, Lo KP, Yulyaningsih E, Craik DJ
Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate. J Biol Chem (2006) 281(12):8224-32: 8224-8232
Chen B, Colgrave ML, Wang C, Craik DJ
Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceae. J Nat Prod (2006) 69: 23-8
Clark RJ, Daly NL, Craik DJ
Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochem J (2006) 394: 85-93
Daly NL, Chen YK, Foley FM, Bansal PS, Bharathi R, Clark RJ, Sommerhoff CP, Craik DJ
The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold J Biol Chem (2006) 281: 23668-75
Daly NL, Clark RJ, Plan MR, Craik DJ
Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif. Biochem J (2006) 393: 619-26
Guo X, Shi J, Tang Z, Cui D, Zhang Y
Synthesis and biological activity of seleno sunflower trypsin inhibitor analog. Chem Biol Drug Des (2006) 68: 341-4
Herrmann A, Svangard E, Claeson P, Gullbo J, Bohlin L, Goransson U
Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2. Cell Mol Life Sci (2006) 63: 235-45
Ireland DC, Colgrave ML, Craik DJ
A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. Biochem J. (2006) 400: 1-12
Ireland DC, Colgrave ML, Nguyencong P, Daly NL, Craik DJ
Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins. J Mol Biol (2006) 357: 1522-35
Morita H, Eda M, Iizuka T, Hirasawa Y, Sekiguchi M, Yun YS, Itokawa H, Takeya K
Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis. Bioorg Med Chem Lett (2006) 16: 4458-4461
Thongyoo P, Tate EW, Leatherbarrow, RJ
Total synthesis of the macrocyclic cysteine knot microprotein MCoTI-II. Chem Commun (2006) 27: 2848-2850
Zablotna E, Kret A, Jaskiewicz A, Olma A, Leplawy MT, Rolka K
Introduction of alpha-hydroxymethyamino acid residues in substrate specificity P1 position of trypsin inhibitor SFTI-1 from sunflower seeds retains its activity. Biochem Biophys Res Commun (2006) 340: 823-8
Avrutina O, Schmoldt H, Gabrijelcic-Geiger D, Le Nguyen D, Sommerhoff CP, Diederichsen U, Kolmar H
Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II. Biol Chem (2005) 386: 1301-6
Chen B, Colgrave ML, Daly NL, Rosengren KJ, Gustafson KR, Craik DJ
Isolation and characterisation of novel cyclotides from viola hederaceae: Solution structure and anti-HIV activity of VHL-1, a leaf-specific-expressed cyclotide. J Biol Chem (2005) 280: 22395-405
Craik DJ, Daly NL
Oxidative folding of the cystine knot motif in cyclotide proteins. Protein Pept Lett (2005) 12: 147-52
Hilpert K, Hansen G, Wessner H, Volkmer-Engert R, Hohne W
Complete substitutional analysis of a sunflower trypsin inhibitor with different serine proteases. J Biochem (Tokyo) (2005) 138: 383-90
Jaulent AM, Brauer AB, Matthews SJ, Leatherbarrow RJ
Solution structure of a novel C2-symmetrical bifunctional bicyclic inhibitor based on SFTI-1. J Biomol NMR (2005) 33: 57-62
Jennings CV, Rosengren KJ, Daly NL, Plan M, Stevens J, Scanlon MJ, Waine C, Norman DG, Anderson MA, Craik DJ
Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Mobius strips exist in nature? Biochemistry (2005) 44: 851-60
Kamimori H, Hall K, Craik DJ, Aguilar MI
Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance. Anal Biochem (2005) 337: 149-53
Korsinczky ML, Clark RJ, Craik DJ
Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1. Biochemistry (2005) 44: 1145-53
Mulvenna JP, Foley FM, Craik DJ.
Discovery, structural determination, and putative processing of the precursor protein that produces the cyclic trypsin inhibitor sunflower trypsin inhibitor 1. J Biol Chem (2005) 280: 32245-53
Mulvenna JP, Sando L, Craik DJ
Processing of a 22 kDa Precursor Protein to Produce the Circular Protein Tricyclon A. Structure (Camb) (2005) 13: 691-701
Simonsen SM, Sando L, Ireland DC, Colgrave ML, Bharathi R, Goransson U, Craik DJ
A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae). Plant Cell (2005) 17: 3176-89
Stawikowski M, Stawikowska R, Jaskiewicz A, Zablotna E, Rolka K
Examples of Peptide-Peptoid Hybrid Serine Protease Inhibitors Based on the Trypsin Inhibitor SFTI-1 with Complete Protease Resistance at the P1-P1' Reactive Site. Chembiochem (2005) 6: 1057-61
Abuja PM, Zenz A, Trabi M, Craik DJ, Lohner K
The cyclic antimicrobial peptide RTD-1 induces stabilized lipid-peptide domains more efficiently than its open-chain analogue. FEBS Lett (2004) 566: 301-6
Barry DG, Daly NL, Bokesch HR, Gustafson KR, Craik DJ
Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework. Structure (Camb) (2004) 12: 85-94
Buffy JJ, McCormick MJ, Wi S, Waring A, Lehrer RI, Hong M
Solid-state NMR investigation of the selective perturbation of lipid bilayers by the cyclic antimicrobial peptide RTD-1. Biochemistry (2004) 43: 9800-12
Colgrave ML, Craik DJ
Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot. Biochemistry (2004) 43: 5965-75
Daly NL, Gustafson KR, Craik DJ
The role of the cyclic peptide backbone in the anti-HIV activity of the cyclotide kalata B1. FEBS Lett (2004) 574: 69-72
Dutton JL, Renda RF, Waine C, Clark RJ, Daly NL, Jennings CV, Anderson MA, Craik DJ
Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins. J Biol Chem (2004) 279: 46858-67
Goransson U, Sjogren M, Svangard E, Claeson P, Bohlin L
Reversible antifouling effect of the cyclotide cycloviolacin O2 against barnacles. J Nat Prod (2004) 67: 1287-90
Goransson U, Svangard E, Claeson P, Bohlin L
Novel strategies for isolation and characterization of cyclotides: the discovery of bioactive macrocyclic plant polypeptides in the Violaceae. Curr Protein Pept Sci (2004) 5: 317-29
Gustafson KR, McKee TC, Bokesch HR
Anti-HIV cyclotides. Curr Protein Pept Sci (2004) 5: 331-40
Hsieh PW, Chang FR, Wu CC, Wu KY, Li CM, Chen SL, Wu YC
New cytotoxic cyclic peptides and dianthramide from Dianthus superbus. J Nat Prod (2004) 67: 1522-1527
Jaulent AM, Leatherbarrow RJ
Design, synthesis and analysis of novel bicyclic and bifunctional protease inhibitors. Protein Eng Des Sel (2004) 17: 681-7
Kawai Y, Ishii Y, Arakawa K, Uemura K, Saitoh B, Nishimura J, Kitazawa H, Yamazaki Y, Tateno Y, Itoh T, Saito T
Structural and functional differences in two cyclic bacteriocins with the same sequences produced by lactobacilli. Appl Environ Microbiol (2004) 70: 2906-11
Kawai Y, Kemperman R, Kok J, Saito T
The circular bacteriocins gassericin A and circularin A. Curr Protein Pept Sci (2004) 5: 393-8
Kawulka KE, Sprules T, Diaper CM, Whittal RM, McKay RT, Mercier P, Zuber P, Vederas JC
Structure of Subtilosin A, a Cyclic Antimicrobial Peptide from Bacillus subtilis with Unusual Sulfur to a-Carbon Cross-Links: Formation and Reduction of a-Thio-a-Amino Acid Derivatives. Biochemistry (2004) 43: 3385-95
Li CQ, Li BG, Qi HY, Li QL, Wang FP, Zhang GL
Three cyclooctapeptides and one glycoside from Microtoena prainiana. J Nat Prod (2004) 67: 978-982
Nourse A, Trabi M, Daly NL, Craik DJ
A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation. J Biol Chem (2004) 279: 562-70
Ohtsuka K, Kajiki R, Waki M, Nojima T, Takenaka S
Immobilization of sunflower trypsin inhibitor (SFTI-1) peptide onto a gold surface and analysis of its interaction with trypsin. Analyst (2004) 129: 888-9
Simonsen SM, Daly NL, Craik DJ
Capped acyclic permutants of the circular protein kalata B1. FEBS Lett (2004) 577: 399-402
Stein T, Dusterhus S, Stroh A, Entian KD
Subtilosin production by two Bacillus subtilis subspecies and variance of the sbo-alb cluster. Appl Environ Microbiol (2004) 70: 2349-53
Svangard E, Goransson U, Hocaoglu Z, Gullbo J, Larsson R, Claeson P, Bohlin L
Cytotoxic cyclotides from Viola tricolor. J Nat Prod (2004) 67: 144-7
Trabi M, Craik DJ
Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1. Plant Cell (2004) 16: 2204-16
Trabi M, Svangard E, Herrmann A, Goransson U, Claeson P, Craik DJ, Bohlin L
Variations in cyclotide expression in viola species. J Nat Prod (2004) 67: 806-10
Wang C, Zhang L-L, Lu Y, Zheng Q-T, Cheng Y-X, Zhou J, Tan N-H
Study on the spatial structure of brachystemin C, a new cyclic peptide from Brachystemma calycinum J Mol Struct (2004) 688: 67-71
Wélé A, Landon C, Labbé H, Vovelle F, Zhang Y, Bodo B
Sequence and solution structure of cherimolacyclopeptides A and B, novel cyclooctapeptides from the seeds of Annona cherimola Tetrahedron (2004) 60: 405-414
Wélé A, Zhang Y, Ndoye I, Brouard JP, Pousset JL, Bodo B
A cytotoxic cyclic heptapeptide from the seeds of Annona cherimola. J Nat Prod (2004) 67: 1577-1579
Barry DG, Daly NL, Clark RJ, Sando L, Craik DJ
Linearization of a naturally occurring circular protein maintains structure but eliminates hemolytic activity. Biochemistry (2003) 42: 6688-95
Daly NL, Clark RJ, Craik DJ
Disulfide folding pathways of cystine knot proteins. Tying the knot within the circular backbone of the cyclotides. J Biol Chem (2003) 278: 6314-22
Goransson U, Broussalis AM, Claeson P
Expression of Viola cyclotides by liquid chromatography-mass spectrometry and tandem mass spectrometry sequencing of intercysteine loops after introduction of charges and cleavage sites by aminoethylation. Anal Biochem (2003) 318: 107-117
Goransson U, Craik DJ
Disulfide mapping of the cyclotide kalata B1. Chemical proof of the cystic cystine knot motif. J Biol Chem (2003) 278: 48188-96
Kalmokoff ML, Cyr TD, Hefford MA, Whitford MF, Teather RM
Butyrivibriocin AR10, a new cyclic bacteriocin produced by the ruminal anaerobe Butyrivibrio fibrisolvens AR10: characterization of the gene and peptide. Can J Microbiol (2003) 49: 763-73
Kemperman R, Jonker M, Nauta A, Kuipers OP, Kok J
Functional analysis of the gene cluster involved in production of the bacteriocin circularin A by Clostridium beijerinckii ATCC 25752. Appl Environ Microbiol (2003) 69: 5839-48
Kemperman R, Kuipers A, Karsens H, Nauta A, Kuipers O, Kok J
Identification and characterization of two novel clostridial bacteriocins, circularin A and closticin 574. Appl Environ Microbiol (2003) 69: 1589-97
Marx UC, Korsinczky ML, Schirra HJ, Jones A, Condie B, Otvos L Jr, Craik DJ
Enzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide. J Biol Chem (2003) 278: 21782-9
Mu Q, Tang WD, Liu RY, Li CM, Lou LG, Sun HD, Hu CQ
Constituents from the Stems of Goniothalamus griffithii Planta Med (2003) 69: 826-830
Napolitano A, Rodriquez M, Bruno I, Marzocco S, Autore G, Riccio R, Gomez-Paloma L
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 Tetrahedron (2003) 59: 10203-10211
Rosengren KJ, Daly NL, Plan MR, Waine C, Craik DJ
Twists, knots, and rings in proteins. Structural definition of the cyclotide framework. J Biol Chem (2003) 278: 8606-16
Sanchez-Barrena MJ, Martinez-Ripoll M, Galvez A, Valdivia E, Maqueda M, Cruz V, Albert A
Structure of bacteriocin AS-48: from soluble state to membrane bound state. J Mol Biol (2003) 334: 541-9
Sonnet P, Da Nascimento S, Marty D, Franceschini D, Guillon J, Brion J-D, Rochette J
First synthesis of segetalins B and G: two cyclopentapeptides with estrogen-like activity Tetrahedron Lett (2003) 44: 3293-3296
Svangard E, Goransson U, Smith D, Verma C, Backlund A, Bohlin L, Claeson P
Primary and 3-D modelled structures of two cyclotides from Viola odorata. Phytochemistry (2003) 64: 135-42
Brauer AB, Kelly G, Matthews SJ, Leatherbarrow RJ
The (1)H-NMR solution structure of the antitryptic core peptide of Bowman-Birk inhibitor proteins: a minimal canonical loop. J Biomol Struct Dyn (2002) 20: 59-70
Bushnell DA, Cramer P, Kornberg RD
Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution. Proc Natl Acad Sci U S A (2002) 99: 1218-1222
Craik DJ, Simonsen S, Daly NL
The cyclotides: novel macrocyclic peptides as scaffolds in drug design. Curr Opin Drug Discov Devel (2002) 5: 251-60
Deechongkit S, Kelly JW
The effect of backbone cyclization on the thermodynamics of beta-sheet unfolding: stability optimization of the PIN WW domain. J Am Chem Soc (2002) 124: 4980-6
Descours A, Moehle K, Renard A, Robinson JA
A new family of beta-hairpin mimetics based on a trypsin inhibitor from sunflower seeds. Chembiochem (2002) 3: 318-23
Lindholm P, Goransson U, Johansson S, Claeson P, Gullbo J, Larsson R, Bohlin L, Backlund A
Cyclotides: a novel type of cytotoxic agents. Mol Cancer Ther (2002) 1: 365-369
Matsumoto T, Nishimura K, Takeya K
New Cyclic Peptides from Citrus medica var. sarcodactylis SWINGLE Chem Pharm Bull (2002) 50: 857-860
Matsumoto T, Tashiro N, Nishimura K, Takeya K
New cyclic peptides from Citrus aurantium Heterocycles (2002) 56: 477-482
Matsumoto T, Tashiro N, Nishimura K, Takeya K
Conformational analysis of cyclolinopeptides A and B Tetrahedron (2002) 58: 5135-5140
Skjeldal L, Gran L, Sletten K, Volkman BF
Refined structure and metal binding site of the kalata B1 peptide. Arch Biochem Biophys (2002) 399: 142-8
Tran D, Tran PA, Tang YQ, Yuan J, Cole T, Selsted ME
Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides. J Biol Chem (2002) 277: 3079-84
Weiss TM, Yang L, Ding L, Waring AJ, Lehrer RI, Huang HW
Two states of cyclic antimicrobial peptide RTD-1 in lipid bilayers. Biochemistry (2002) 41: 10070-6
Williams NK, Prosselkov P, Liepinsh E, Line I, Sharipo A, Littler DR, Curmi PM, Otting G, Dixon NE
In vivo protein cyclization promoted by a circularly permuted Synechocystis sp. PCC6803 DnaB mini-intein. J Biol Chem (2002) 227: 7790-8
Zablotna E, Kazmierczak K, Jaskiewicz A, Stawikowski M, Kupryszewski G, Rolka K
Chemical synthesis and kinetic study of the smallest naturally occurring trypsin inhibitor SFTI-1 isolated from sunflower seeds and its analogues. Biochem Biophys Res Commun (2002) 292: 855-9
Bokesch HR, Pannell LK, Cochran PK, Sowder RC 2nd, McKee TC, Boyd MR
A novel anti-HIV macrocyclic peptide from Palicourea condensata. J Nat Prod (2001) 64: 249-50
Broussalis AM, Goransson U, Coussio JD, Ferraro G, Martino V, Claeson P
First cyclotide from Hybanthus (Violaceae). Phytochemistry (2001) 58: 47-51
Camarero JA, Fushman D, Sato S, Giriat I, Cowburn D, Raleigh DP, Muir TW
Rescuing a destabilized protein fold through backbone cyclization. J Mol Biol (2001) 308: 1045-62
Craik DJ
Plant cyclotides: circular, knotted peptide toxins. Toxicon (2001) 39: 1809-13
Felizmenio-Quimio ME, Daly NL, Craik DJ
Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis. J Biol Chem (2001) 276: 22875-82
Heitz A, Hernandez JF, Gagnon J, Hong TT, Pham TT, Nguyen TM, Le-Nguyen D, Chiche L
Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins. Biochemistry (2001) 40: 7973-83
Jennings C, West J, Waine C, Craik D, Anderson M
Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis. Proc Natl Acad Sci U S A (2001) 98: 10614-9
Korsinczky ML, Schirra HJ, Rosengren KJ, West J, Condie BA, Otvos L, Anderson MA, Craik DJ
Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant. J Mol Biol (2001) 311: 579-91
Long YQ, Lee SL, Lin CY, Enyedy IJ, Wang S, Li P, Dickson RB, Roller PP
Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase. Bioorg Med Chem Lett (2001) 11: 2515-9
Matsumoto T, Shishido A, Morita H, Itokawa H, Takeya K
Cyclolinopeptides F–I, cyclic peptides from linseed Phytochemistry (2001) 57: 251-260
Sonnet P, Petit L, Marty D, Guillon J, Rochettea J, Brion J-D
First synthesis of segetalin A and analogous cyclohexapeptides Tetrahedron Lett (2001) 42: 1681-1683
Trabi M, Schirra HJ, Craik DJ
Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes. Biochemistry (2001) 40: 4211-21
Baraguey C, Blond A, Correia I, Pousset J-L, Bodo B, Auvin-Guette C
Mahafacyclin A, a cyclic heptapeptide from Jatropha mahafalensis exhibiting β-bulge conformation Tetrahedron Lett (2000) 41: 325-329
Daly NL, Craik DJ
Acyclic permutants of naturally occurring cyclic proteins. Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1. J Biol Chem (2000) 275: 19068-75
Ding Z-T, Zhou J, Tan N-H, Teng R
Two New Cyclic Peptides from Drymaria diandra Planta Med (2000) 66: 386-386
Gonzalez C, Langdon GM, Bruix M, Galvez A, Valdivia E, Maqueda M, Rico M
Bacteriocin AS-48, a microbial cyclic polypeptide structurally and functionally related to mammalian NK-lysin. Proc Natl Acad Sci U S A (2000) 97: 11221-6
Gran L, Sandberg F, Sletten K
Oldenlandia affinis (R&S) DC. A plant containing uteroactive peptides used in African traditional medicine. J Ethnopharmacol (2000) 70: 197-203
Gustafson KR, Walton LK, Sowder RC Jr, Johnson DG, Pannell LK, Cardellina JH Jr, Boyd MR
New circulin macrocyclic polypeptides from Chassalia parvifolia. J Nat Prod (2000) 63: 176-8
Hallock YF, Sowder RC 2nd, Pannell LK, Hughes CB, Johnson DG, Gulakowski R, Cardellina JH 2nd, Boyd MR
Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa. J Org Chem (2000) 65: 124-8
Hernandez JF, Gagnon J, Chiche L, Nguyen TM, Andrieu JP, Heitz A, Trinh Hong T, Pham TT, Le Nguyen D
Squash trypsin inhibitors from Momordica cochinchinensis exhibit an atypical macrocyclic structure. Biochemistry (2000) 39: 5722-30
Auvin-Guette C, Baraguey C, Blond A, Xavier HS, Pousset J-L, Bodo B
Pohlianins A, B and C, cyclic peptides from the laxes of Jatropha pohliana ssp. molissima Tetrahedron (1999) 55: 11495-11510
Camarero JA, Muir TW
Biosynthesis of a Head-to-Tail Cyclized Protein with Improved Biological Activity. J Am Chem Soc (1999) 121: 5597-8
Craik DJ, Daly NL, Bond T, Waine C
Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif. J Mol Biol (1999) 294: 1327-36
Daly NL, Koltay A, Gustafson KR, Boyd MR, Casas-Finet JR, Craik DJ
Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity. J Mol Biol (1999) 285: 333-45
Daly NL, Love S, Alewood PF, Craik DJ
Chemical synthesis and folding pathways of large cyclic polypeptides: studies of the cystine knot polypeptide kalata B1. Biochemistry (1999) 38: 10606-14
Goransson U, Luijendijk T, Johansson S, Bohlin L, Claeson P
Seven novel macrocyclic polypeptides from Viola arvensis. J Nat Prod (1999) 62: 283-6
Iwai H, Pluckthun A
Circular beta-lactamase: stability enhancement by cyclizing the backbone. FEBS Lett (1999) 459: 166-72
Li C-M, Tan N-H, Zheng H-L, Mu Q, Hao X-J, He Y-N, Zhou J
Cyclopeptides from the seeds of Annona glabra Phytochemistry (1999) 50: 1047-1052
Luckett S, Garcia RS, Barker JJ, Konarev AV, Shewry PR, Clarke AR, Brady RL
High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds. J Mol Biol (1999) 290: 525-33
Morita H, Sato Y, Kobayashi J
Cyclosquamosins A – G, cyclic peptides from the seeds of Annona squamosa Tetrahedron (1999) 55: 7509-7518
Morita H, Shishido A, Matsumoto T, Itokawa H, Takeya K
Cyclolinopeptides B - E, new cyclic peptides from Linum usitatissimum Tetrahedron (1999) 55: 967-976
Tam JP, Lu YA, Yang JL, Chiu KW
An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides. Proc Natl Acad Sci U S A (1999) 96: 8913-8
Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME
A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science (1999) 286: 498-502
Kawai Y, Saito T, Kitazawa H, Itoh T
Gassericin A; an uncommon cyclic bacteriocin produced by Lactobacillus gasseri LA39 linked at N- and C-terminal ends. Biosci Biotechnol Biochem (1998) 62: 2438-40
Kawai Y, Saito T, Suzuki M, Itoh T
Sequence analysis by cloning of the structural gene of gassericin A, a hydrophobic bacteriocin produced by Lactobacillus gasseri LA39. Biosci Biotechnol Biochem (1998) 62: 887-92
Langdon GM, Bruix M, Galvez A, Valdivia E, Maqueda M, Rico M
Sequence-specific 1H assignment and secondary structure of the bacteriocin AS-48 cyclic peptide. J Biomol NMR (1998) 12: 173-5
Li C-M, Tan N-H, Mu Q, Zheng H-L, Hao X-J, Liang H-L, Zhou J
Cyclopeptides from the seeds of Annona glabra Phytochemistry (1998) 47: 1293-1296
Li C-M, Tan N-H, Zheng H-L, Mu Q, Hao X-J, He Y-N, Zhou J
Cyclopeptide from the seeds of Annona muricata Phytochemistry (1998) 48: 555-556
Tam JP, Lu YA
A biomimetic strategy in the synthesis and fragmentation of cyclic protein. Protein Sci (1998) 7: 1583-92
Wang Y-C, Tan N-H, Zhou J, Wu H-M
Cyclopeptides from dianthus superbus Phytochemistry (1998) 49: 1453-1456
Auvin C, Baraguey C, Blond A, Lezenven F, Pousset J-L, Bodo B
Curcacycline B, a cyclic nonapeptide from Jatropha curcas enhancing rotamase activity of cyclophilin Tetrahedron Lett (1997) 38: 2845-2848
Auvin-Guette C, Baraguey C, Blond A, Pousset J-L, Bodo B
Cyclogossine B, a Cyclic Octapeptide from Jatropha gossypifolia J Nat Prod (1997) 60: 1155-1157
Li C-M, Tan N-H, Mu Q, Zheng H-L, Hao X-J, Wu Y, Zhou J
Cyclopeptide from the seeds of Annona squamosa Phytochemistry (1997) 45: 521-523
Morita H, Gonda A, Takeya k, Itokawa H, Hirano T, Oka K, Shirota O
Solution state conformation of an immunosuppressive cyclic dodecapeptide, cycloleonurinin Tetrahedron (1997) 53: 7469-7478
Morita H, Gonda A, Takeya K, Itokawa H, Iitaka Y
Cycloleonuripeptide D, a new proline-rich cyclic decapeptide from Leonurus heterophyllus Tetrahedron (1997) 53: 1617-1626
Morita H, Gonda A, Takeya k, Itokawa H, Shirota O
Conformational Preferene of Cycloleonuripeptides A, B, and C, Three Proline-Rich Cyclic Nonapeptides from Leonurus heterophyllus Chem Pharm Bull (1997) 45: 161-164
Morita H, Kayashita T, Takeya K, Itokawa H, Shiro M
Conformation of cyclic heptapeptides: solid and solution state conformation of yunnanin A Tetrahedron (1997) 53: 1607-1616
Morita H, Kayashita T, Uchida A, Takeya K, Itokawa H
Cyclic Peptides from Higher Plants. 33. Delavayins A−C, Three New Cyclic Peptides from Stellaria delavayi J Nat Prod (1997) 60: 212-215
Morita H, Shishido A, Kayashita T, Takeya K, Itokawa H
Cyclic Peptides from Higher Plants. 39. Dichotomins F and G, Cyclic Peptides from Stellaria dichotoma var. lanceolata J Nat Prod (1997) 60: 404-407
Morita H, Takeya K, Itokawa H
Cyclic octapeptides from Stellaria dichotoma var. lanceolata Phytochemistry (1997) 45: 841-845
Morita H, Yun YS, Takeya K, Itokawa H
Conformation of cyclic heptapeptides: Conformational analysis of segetalins D and E by distance geometry calculations Chem Pharm Bull (1997) 45: 883-887
Morita H, Yun YS, Takeya K, Itokawa H, Shirota O
Thionation of segetalins A and B, cyclic peptides with estrogen-like activity from seeds of Vaccaria segetalis Bioorg Med Chem (1997) 5: 631-636
Yun YS, Morita H, Takeya K, Itokawa H
Cyclic peptides from higher plants. 34. Segetalins G and H, structures and estrogen-like activity of cyclic pentapeptides from Vaccaria segetalis. J Nat Prod (1997) 60: 216-218
Zhao Y-R, Zhou J, Wang X-K, Wu H-M, Huang X-L, Zou C
Three cyclopeptides from Stellaria delavayi Phytochemistry (1997) 46: 709-714
Derua R, Gustafson KR, Pannell LK
Analysis of the disulfide linkage pattern in circulin A and B, HIV-inhibitory macrocyclic peptides. Biochem Biophys Res Commun (1996) 228: 632-8
Horsten SFAJ, van den Berg AJJ, Kettenes-van den Bosch JJ, Leeflang BR, Labadie RP
Cyclogossine A: A Novel Cyclic Heptapeptide Isolated from the Latex of Jatropha gossypifolia Planta Med (1996) 62: 46-50
Morita H, Kayashita T, Shimomura M, Takeya K, Itokawa H
Cyclic Peptides from Higher Plants. 24.1 Yunnanin C, a Novel Cyclic Heptapeptide from Stellaria yunnanensis J Nat Prod (1996) 59: 280-282
Morita H, Kayashita T, Shishido A, Takeya K, Itokawa H, Shiro M
Dichotomins A - E, new cyclic peptides from stellaria dichotoma L. var. lanceolata Bge. Tetrahedron (1996) 52: 1165-1176
Morita H, Yun YS, Takeya K, Itokawa H, Shirota O
A cyclic heptapeptide from Vaccaria segetalis Phytochemistry (1996) 42: 439-441
Van den Berg AJJ, Horsten SFAJ, Kettenes-van den Bosch JJ, Beukelman CJ, Kroes BH, Leeflang BR, Labadie RP
Podacycline A and B, two cyclic peptides in the latex of Jatropha podagrica Phytochemistry (1996) 42: 129-133
Itokawa H, Yun Y, Morita H, Takeya K, Yamada K
Estrogen-like activity of cyclic peptides from Vaccaria segetalis extracts. Planta Med (1995) 61: 561-562
Itokawa H, Yun Y, Morita H, Takeya K, Yamada K
Estrogen-like activity of cyclic peptides from Vaccaria segetalis extracts Planta Med (1995) 61: 561-562
Morita H, Kayashita T, Takeya K, Itokawa H
Cyclic Peptides from Higher Plants, Part 15, Pseudostellarin H, a New Cyclic Octapeptide from Pseudostellaria heterophylla J Nat Prod (1995) 58: 943-947
Morita H, Kayashita T, Takeya K, Itokawa H, Shiro M
Crystal and solution forms of a cyclic heptapeptide, pseudostellarin D1) Tetrahedron (1995) 51: 12539-12548
Morita H, Yun YS, Takeya K, Itokawa H, Shiro M
Conformational analysis of a cyclic hexapeptide, segetalin A from Vaccaria segetalis Tetrahedron (1995) 51: 5987-6002
Morita H, Yun YS, Takeya K, Itokawa H, Yamada K
Segetalins B, C and D, three new cyclic peptides from Vaccaria segetalis Tetrahedron (1995) 51: 6003-6014
Saether O, Craik DJ, Campbell ID, Sletten K, Juul J, Norman DG
Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1. Biochemistry (1995) 34: 4147-58
van den Berg AJ, Horsten SF, Kettenes-van den Bosch JJ, Kroes BH, Beukelman CJ, Leeflang BR, Labadie RP
Curcacycline A--a novel cyclic octapeptide isolated from the latex of Jatropha curcas L. FEBS lett (1995) 385: 215-218
Zhao Y-R, Zhou J, Wang X-K, Huang X-L, Wu H-M, Zou C
Cyclopeptides from Stellaria yunnanensis Phytochemistry (1995) 40: 1453-1456
Gustafson KR, Sowder RC, Henderson LE, Parsons IC, Kashman Y, Cardellina JH, McMahon JB, Buckheit RB, Pannell LK, Boyd MR
Circulins A and B. Novel human immunodeficiency virus (HIV)-inhibitory macrocyclic peptides from the tropical tree Chassalia parvifolia. J Am Chem Soc (1994) 116: 9338-8
Kawai Y, Saito T, Toba T, Samant SK, Itoh T
Isolation and characterization of a highly hydrophobic new bacteriocin (gassericin A) from Lactobacillus gasseri LA39. Biosci Biotechnol Biochem (1994) 58: 1218-21
Martinez-Bueno M, Maqueda M, Galvez A, Samyn B, Van Beeumen J, Coyette J, Valdivia E
Determination of the gene sequence and the molecular structure of the enterococcal peptide antibiotic AS-48. J Bacteriol (1994) 176: 6334-9
Morita H, Kayashita T, Kobata H, Gonda A, Takeya K, Itokawa H
Pseudostellarins A - C, new tyrosinase inhibitory cyclic peptides from Pseudostellaria heterophylla Tetrahedron (1994) 50: 6797-6804
Morita H, Kayashita T, Kobata H, Gonda A, Takeya K, Itokawa H
Pseudostellarins D - F, new tyrosinase inhibitory cyclic peptides from Pseudostellaria heterophylla Tetrahedron (1994) 50: 9975-9982
Morita H, Kayashita T, Takeya K, Itokawa H
Conformational analysis of a tyrosinase inhibitory cyclic pentapeptide, pseudostellarin A, from Pseudostellaria heterophylla Tetrahedron (1994) 50: 12599-12608
Morita H, Kobata H, Takeya K, Itokawa H
Pseudostellarin G, a new tyrosinase inhibitory cyclic octapeptide from Pseudostellaria heterophylla Tetrahedron Lett (1994) 35: 3563-3564
Morita H, Yun YS, Takeya K, Itokawa H
Segetalin A, a new cyclic hexapeptide from Vaccaria segetalis Tetrahedron Lett (1994) 35: 9593-9596
Samyn B, Martinez-Bueno M, Devreese B, Maqueda M, Galvez A, Valdivia E, Coyette J, Van Beeumen J
The cyclic structure of the enterococcal peptide antibiotic AS-48. FEBS Lett (1994) 352: 87-90
Witherup KM, Bogusky MJ, Anderson PS, Ramjit H, Ransom RW, Wood T, Sardana M
Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes. J Nat Prod (1994) 57: 1619-25
Schopke T, Hasan Agha MI, Kraft R, Otto A, Hiller K
Hämolytisch aktive komponenten aus Viola tricolor L. und Viola arvensis Murray. [In German] Sci Pharm (1993) 61: 145-53
Tan N-H, Zhou J, Chen C-X, Zhao S-X
Cyclopeptides from the roots of Pseudostellaria heterophylla Phytochemistry (1993) 32: 1327-1330
Kinoshita K, Tanaka J, Kuroda K, Koyama K, Natori S, Kinoshita T
Cycloleonurinin, a Cyclic Peptide from Leonuri Fructus Chem Pharm Bull (1991) 39: 712-715
Matsubara Y, Yusa T, Sawabe A, Iizuka Y, Takekuma S, Yoshida Y
Structures of New Cyclic Peptides in Young Unshiu (Citrus unshiu MARCOV.), Orange (Citrus sinensis OSBECK.) and Amanatsu (Citrus natsudaidai) Peelings Agric Biol Chem (1991) 55: 2923-2929
Toba T, Samant SK, Yoshioka E, Itoh T
Reutericin 6, a new bacteriocin produced by Lactobacillus reuteri LA6. Lett Appl Microbiol (1991) 13: 281-6
Bashwira S, Hootelé C, Tourwé D, Pepermans H, Laus G, Van Binst G
Cleromyrine I, a new cyclohexapeptide from clerodendrum myricoides Tetrahedron (1989) 45: 5845-5852
Blasio BD, Rossi F, Benedetti E, Pavone V, Pedone C, Temussi PA, Zanotti G, Tancredi T
Bioactive peptides: solid-state and solution conformation of cyclolinopeptide A J Am Chem Soc (1989) 111: 9089-9098
Galvez A, Valdivia E, Martinez M, Maqueda M
Bactericidal action of peptide antibiotic AS-48 against Escherichia coli K-12. Can J Microbiol (1989) 35: 318-21
Kosasi S, van der Sluis WG, Boelens R, Hart LA, Labadie RP
Labaditin, a novel cyclic decapeptide from the latex of Jatropha multifida L. (Euphorbiaceae): Isolation and sequence determination by means of two-dimensional NMR FEBS lett (1989) 256: 91-96
Galvez A, Valdivia E, Maqueda M, Montoya E
Production of bacteriocin-like substances by group D streptococci of human origin. Microbios (1985) 43: 223-32
Goldenberg DP, Creighton TE
Circular and circularly permuted forms of bovine pancreatic trypsin inhibitor. J Mol Biol (1983) 165: 407-13
Wieland T, Faulstich H
Amatoxins, phallotoxins, phallolysin, and antamanide: the biologically active components of poisonous Amanita mushrooms. CRC Crit Rev Biochem (1978) 5: 185-260
Levesque MP, Twigg RW, Motley T, Katari MS, Dedhia NN, O'Shaughnessy AL, Balija V, Martienssen RA, McCombie RW, Benfey P, Stevenson D (Unpublished)
Levesque MP, Twigg RW, Motley T, Katari MS, Dedhia NN, O'Shaughnessy AL, Balija V, Martienssen RA, McCombie RW, Benfey P, Stevenson D (Unpublished)
Zhang J, Shu W, Liao B (Unpublished)