MCo-CVX-5c(842) Protein Card

General Information
Name MCo-CVX-5c
Sequence VCPKILQRCRRDSDCPGACICRGNGYCGSYRXCRGpRRBC
YXK
Class Squash trypsin inhibitor
Average Mass 4448.17
Monoisotopic Mass 4444.99
m/z M+H 4448.17
ProteinType Grafted
Parent MCoTI-I
Organism Synthetic
Notes B, X and p represent the amino acid, 2-naphthylalanine, citruline and D-proline, respectively.
Cyclic Yes

Assay
No assays found

References
Aboye,T.L., Ha,H., Majumder,S., Christ,F., Debyser,Z., Shekhtman,A., Neamati,N. and Camarero,J.A. (2012) Design of a novel cyclotide-based CXCR4 antagonist with anti-human immunodeficiency virus (HIV)-1 activity. J. Med. Chem. 55:10729-10734
Lesniak, W.G., Aboye, T., Chatterjee, S., Camarero, J.A. and Nimmagadda, S. (2017) In vivo evaluation of an engineered cyclotide as specific CXCR4 imaging reagent Chemistry‚ÄďA European Journal 23:14469-14475

Cross-references
Nucleic acids
Structure
Links

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