cyclolinopeptide A(703) Protein Card

General Information
Name cyclolinopeptide A
Alternative name(s) [1-9-NaC]-CLA,[1–9-NαC]-linusorb B3
Sequence PPFFLIILV
Class Orbitide
Average Mass 1040.36
Monoisotopic Mass 1039.65
m/z M+H 1040.65
ProteinType Wild type
Parent
Organism Linum usitatissimum (flax)
Notes
Cyclic Yes

Assay
Cancer Cell Toxicity
cyclolinopeptide A and B exhibited apoptosis induction on SGC-7901 cells. [...]Zou et al. (2018) Journal of Functional Foods 48:692-703

References
Morita H, Shishido A, Matsumoto T, Itokawa H, Takeya K (1999) Cyclolinopeptides B - E, new cyclic peptides from Linum usitatissimum Tetrahedron 55:967-976
Matsumoto T, Shishido A, Morita H, Itokawa H, Takeya K (2001) Cyclolinopeptides F–I, cyclic peptides from linseed Phytochemistry 57:251-260
Matsumoto T, Nishimura K, Takeya K (2002) New Cyclic Peptides from Citrus medica var. sarcodactylis SWINGLE Chem Pharm Bull 50:857-860
Blasio BD, Rossi F, Benedetti E, Pavone V, Pedone C, Temussi PA, Zanotti G, Tancredi T (1989) Bioactive peptides: solid-state and solution conformation of cyclolinopeptide A J Am Chem Soc 111:9089-9098
Okinyo‐Owiti, D.P., Young, L., Burnett, P.G.G. and Reaney, M.J. (2014) New flaxseed orbitides: Detection, sequencing, and 15N incorporation Peptide Science 102:168-175
Zou, X.G., Hu, J.N., Li, J., Yang, J.Y., Du, Y.X., Yu, Y.F. and Deng, Z.Y (2018) iCellular uptake of [1–9-NαC]-linusorb B2 and [1–9-NαC]-linusorb B3 isolated from flaxseed, and their antitumor activities in human gastric SGC-7901 cells Journal of Functional Foods 48:692-703

Cross-references
Nucleic acids
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