psyle C(554) Protein Card

General Information
Name psyle C
Sequence KLCGETCFKFKCYTPGCSCSYFPCK
Class Cyclotide
Average Mass 2838.36
Monoisotopic Mass 2836.17
m/z M+H 2837.18
ProteinType Wild type
Parent
Organism Psychotria leptothyrsa
Notes Linear cyclotide
Cyclic No

Assay
Cancer Cell Toxicity
Psyle A, psyle C, psyle E and cycloviolacin O2 shown to possess cytotoxic activity in cancer cells. [...]Gerlach SL et al. (2010) Biopolymers 94:617-625
Nonclonogenic fluorometric microculture cytotoxicity assay was performed on psyle A, C and E using U-937 GTB human lymphoma tumor cell line. [...]Gerlach SL et al. (2010) J Nat Prod 73:1207-1213

References
Gerlach SL, Burman R, Bohlin L, Mondal D, Göransson U (2010) Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa J Nat Prod 73:1207-1213
Gerlach SL, Rathinakumar R, Chakravarty G, Göransson U, Wimley WC, Darwin SP, Mondal D (2010) Anticancer and chemosensitizing abilities of cycloviolacin 02 from Viola odorata and psyle cyclotides from Psychotria leptothyrsa. Biopolymers 94:617-625

Cross-references
Nucleic acids
Structure
Links

Tools