[P20D,V21K]-kalata B1(234) Protein Card

General Information
Name [P20D,V21K]-kalata B1
Sequence GLPVCGETCVGGTCNTPGCTCSWDKCTRN
Class Cyclotide
Average Mass 2939.29
Monoisotopic Mass 2937.14
m/z M+H 2938.15
ProteinType Mutant
Parent kalata B1
Organism Synthetic
Notes Mutant of kalata B1
Cyclic Yes

Assay
Hemolytic
Both [P20D/V21K]kalata B1 and [W19K/P20N/V21K]kalata B1 exhibited no haemolytic activity. Kalata B1 exhibited mild haemolytic activity. [...]Clark RJ et al. (2006) Biochem J 394:85-93

References
Clark RJ, Daly NL, Craik DJ (2006) Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochem J 394:85-93

Cross-references
Nucleic acids
Structure Solution structure of [P20D,V21K]-kalata B1
Links

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