violacin A(172) Protein Card

General Information
Name violacin A
Class Cyclotide
Average Mass 3006.51
Monoisotopic Mass 3004.26
m/z M+H 3005.27
ProteinType Wild type
Organism Viola odorata
Psychotria leptothyrsa
Notes linear cyclotide
Cyclic No

Chemical Shift
Chemical shift data for violacin A [...]Ireland DC et al. (2006) J Mol Biol 357:1522-35
Enzymatic Digest
violacin A was impervious to digestion by the endopeptidases trypsin and thermolysin following incubation for 6 h [...]Ireland DC et al. (2006) J Mol Biol 357:1522-35
Violacin A showed markedly decreased hemolytic activity relative to the prototypic cyclotide kalata B1 [...]Ireland DC et al. (2006) J Mol Biol 357:1522-35

Ireland DC, Colgrave ML, Nguyencong P, Daly NL, Craik DJ (2006) Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins. J Mol Biol 357:1522-35
Ireland DC, Colgrave ML, Craik DJ (2006) A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability. Biochem J. 400:1-12
Gerlach SL, Burman R, Bohlin L, Mondal D, Göransson U (2010) Isolation, characterization, and bioactivity of cyclotides from the Micronesian plant Psychotria leptothyrsa J Nat Prod 73:1207-1213

Protein precursor(s) violacin A precursor
Nucleic acids violacin A precursor
Structure violacin A
Links GenBank Q2HY54.1
SwissProt Q2HY54