cycloviolacin H3(139) Protein Card

General Information
Name cycloviolacin H3
Sequence GLPVCGETCFGGTCNTPGCICDPWPVCTRN
Class Cyclotide
Average Mass 3077.50
Monoisotopic Mass 3075.23
m/z M+H 3076.23
ProteinType Wild type
Parent
Organism Viola hederacea
Notes
Cyclic Yes

Assay
Nematocidal
A range of natural variants were selected based on net charge and/or hydrophobicity and were tested alongside the prototypic cyclotide kB1 in larval development assays with H. contortus and T. colubriformis. [...]Colgrave ML et al. (2008) Chembiochem 9:1939-1945

References
Chen B, Colgrave ML, Daly NL, Rosengren KJ, Gustafson KR, Craik DJ (2005) Isolation and characterisation of novel cyclotides from viola hederaceae: Solution structure and anti-HIV activity of VHL-1, a leaf-specific-expressed cyclotide. J Biol Chem 280:22395-405

Cross-references
Nucleic acids
Structure
Links SwissProt P85232

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